Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How you will Achieve More with Intellia:
As an Associate Director, you will join the Analytical Development team within the Technical Operations group and embrace the opportunity to transform amazing sciences and technologies into powerful cures. As a senior member of the analytical development department, you will be overseeing the design, development, and execution of multiple AAV serotype-based analytical chromatography and biophysical characterization methods to quantitate and characterize a variety of molecular targets relevant to the manufacturing and testing of gene therapy and cell therapy platforms. Main responsibilities also include:
Functions independently as the technical expert in chromatography and biophysical characterization method development, execution and troubleshooting including but not limited to RP-HPLC, IEX-HPLC, CE-SDS, cIEF (R, NR) AUC, DLS, Mass spectrometry as it related to AAV viral products
Assists in the execution of analytical development activities at CROs and CMOs, including deliverables and timelines; participate in tech transfer of intellectual property, protocols/procedures and know-how from internal labs to QC and CMOs/CROs, or between CMOs/CROs
Defines science-driven, phase appropriate, and risk-based analytical development strategies to support the development candidate during advancing clinical development stages
Assists in review and writing of regulatory filings including IND/IMPD and BLA
Are you interested in working in the analytical development group? Are you skilled in analytical method development focused on AAV? If you say yes, we encourage you to apply! Other qualifications and desired skills include:
Ph.D. in chemistry, biology, biochemistry or related field and 6+ years of experience or Masters’ degree and 10+ years experience in analytical development within a biotech/pharmaceutical analytical development and/or Quality Control environment required
Must have experience with AAV gene therapy. Cell therapy, LNP and mRNA experience a plus
Must have experience with regulatory submissions
Knowledge of GMP as relevant to laboratory practices in sample handling and analysis of GLP and GMP samples
Knowledge of industry USP/ICH guidances for the development, qualification/ validation of analytical methods
skills; adaptive learning, critical thinking, and the ability to work well in a team
Meet your future team:
The Analytical Development team is a group of energetic, brilliant and motivated individuals. We work on different modalities and still work as a team to achieve our goals. We are a small but growing family. This group is responsible for developing robust and innovative analytical methods to support internal and external manufacturing processes. We support Intellia’s clinical programs as well as in vivo and ex vivo emerging pipelines. While much of the day-to-day operations require wet-lab work, our team focus is on not only building everyone’s technical expertise but also fostering an environment for career growth as scientists and engineers in biopharmaceutical industry.
You will report to the Senior Director, Analytical Development. She loves to see people grow and develop and look forward to learning from your experiences and building the team together with you.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.