Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How you will Achieve More with Intellia:
We are looking to hire an Associate Director to serve as Toxicology Lead, to support an expanding development pipeline with scientists to characterize the toxicity of their innovative products. You will have opportunities to lead basic research initiatives while gaining broad experience supporting nonclinical development of CRISPR-derived cell therapy and gene editing products. As Toxicology Lead, you will provide strategic expertise and representation for clinical development programs from FIH-enabling through marketing. Additional role responsibilities include:
Effectively interact with other functional area experts in a program team environment to recommend the best course of action for a given program, and defend those recommendations to internal governance committees
Review study designs and ensures interdependencies (e.g., Research, Bioanalytical, TechOps, Pathology, Quality) are aligned with emphasis on appropriate and efficient safety evaluations
Serve as subject matter expert to provide input on other programs and studies, including external partnerships and business development opportunities.
Contributes investigative insight to confirm proof-of-mechanism, proof-of-therapeutic concept and prioritize experimental options to guide effective dosing approaches
Represents Intellia on partnered programs and at external venues such as scientific meetings
Succinctly and effectively communicates interpretation of nonclinical studies for regulatory submissions, including components for IBs and clinical protocols
Interact with Health Authorities, in writing and verbally, including pre-submission (e.g., pre-IND), scientific advice filings, IND or CTA, meeting briefing books, or other requests from global regulatory authorities
Provide mentorship to scientists within and outside of the department and may be responsible for the supervision of internal scientific staff or contracted staff (as needed).
Our ideal candidates will be enthusiastic, entrepreneurial scientists motivated to shape how gene editing benefits patients. A Ph.D. or equivalent experience in Toxicology or closely related field is required, along with experience in the pharmaceutical industry with a proven track record of conducting nonclinical safety assessment studies. Additional role requirements include:
Experience managing multiple drug development programs and priorities, studies, external CRO management
Excellent oral and written communication capabilities to facilitate sharing of information/study results and guide next steps based on data and/or changes in strategy
Familiarity with ICH-guided, GLP-compliant nonclinical study design and conduct
Meet your future team:
This is an excellent opportunity to join the growing Pharmacology & Toxicology team in a highly collaborative organization. This position reports to the Head of Pharmacology & Toxicology. The Pharm/Tox team at Intellia is a group of scientists with diverse backgrounds. You will have the opportunity to shape the regulatory strategy for cell and gene therapy products, incorporating evolving regulatory requirements, and contribute to IND/CTA filings.
Our team is based in Cambridge, MA, and hope that you are accessible to the Cambridge area or willing to relocate. If you decide to join us, you can expect to become a highly valued member of a hardworking and collaborative team. We look forward to fostering your skills, learning from your experiences, and building a larger team together to impact patients’ lives.
Covid-19 Vaccination Policy: Effective Monday, January 3, 2022, all Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. Requests for exemption for medical or sincerely held religious beliefs will be considered.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.