Cell Therapy:
Associate Scientist, Target Discovery

Why Join Intellia? 

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. 

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. 

We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.   

How You Will Achieve More With Intellia:

Communicate research findings with internal teams. Design, conduct and troubleshoot experiments to achieve research goals. Isolate primary human T cells from PBMCs and expand in culture. Evaluate various T cell properties by flow cytometry, cytokine release, RNAseq, etc. Modify T cells using lentiviral vectors and/or CRISPR-based gene editing. Use modified T cells in various cell-based screens to identify novel immune enhancing edits. Position is fixed based in Cambridge, MA office/laboratory; however, telecommuting from a home office is occasionally allowed.

About You:

Requires a Bachelor’s degree in Biochemistry, Pharmaceutical Sciences, Molecular Biology, or a directly related field plus five (5) years of industry and hands-on laboratory experience.

Must have two (2) years of experience with the following (experience may be gained concurrently):

  • Experience working with primary mouse or human T cells, including isolating and culturing primary human T cells from PBMCs and viral transduction of T cells

  • Experience with multicolor flow cytometry and fluorescent cell imaging techniques, including extracellular and intracellular staining of immune cells to profile cellular identity and/or evaluate proteins of interest using a CytoFLEX Benchtop analyzer or similar flow cytometry system, standard flow cytometry-based quantification of fluorescently labeled cells as a marker of genetically engineered cells, and standard fluorescent microscopy techniques to monitor the expression of fluorescent fusion proteins in live cells over time

  • Experience with standard molecular biology techniques, including PCR, ELISA, or western blot

Will accept a Master’s degree + two (2) years of industry and hands-on laboratory experience in lieu of Bachelor’s + five (5) years of described experience.

Location: Cambridge, MA

40 hours per week

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Covid-19 Vaccination Policy: All Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. This requirement includes a booster dose once eligible. Requests for exemption for medical or sincerely held religious beliefs will be considered.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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