Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How you will Achieve More with Intellia:
We are seeking an experienced and motivated Director to join our Pharmacology & Toxicology team at the industry’s leading gene editing company. This role will oversee a team of scientists responsible for Pharm/Tox development strategy. The team also oversees definitive studies in support of advancing new products into clinical trials. The scope of responsibility will span our entire spectrum of genome editing products, including in vivo and cell therapies. The Director will play a key role enabling regulatory filings, such as seeking scientific advice, Investigational New Drug (IND) applications and Clinical Trial Applications (CTA).
Lead and manage a team of scientists in the pharmacology and toxicology department to advance candidate product development programs.
Lead or oversee nonclinical development strategy to comprehensively characterize the safety and efficacy of investigational genome editing products or genome edited cell therapies.
Oversee and manage CROs to ensure the successful design and completion of high-quality nonclinical studies to characterize the safety and efficacy of new products.
Organize and collaborate with cross-functional teams, including in vivo and ex vivo research and development, genomics, regulatory affairs, and manufacturing
Evaluate and interpret data, and clearly communicate recommendations based on results to all levels of the organization.
Ensure compliance with regulatory requirements and industry standards for both LNP and cell therapy programs.
Assist in the preparation and review of regulatory filings, such as IND and CTA, related to LNP and cell therapy programs
Stay current with the latest developments in pharmacology and toxicology, and implement best practices in the department, especially related to LNP and cell therapy programs
Mentor and develop team members to achieve their full potential
PhD in Pharmacology, Toxicology or related field with a strong focus on toxicology
At least 7 years of experience in a leadership role within the pharmaceutical or biotech industry, with experience in LNP and cell therapy programs
Strong understanding of pharmacology and toxicology principles and practices, specifically related to LNP and cell therapy
Experience managing and overseeing CROs, specifically for LNP and cell therapy programs
Excellent interpersonal and communication skills
Ability to lead cross-functional teams and drive high-quality projects to successful completion, specifically related to LNP and cell therapy programs
Strong organizational and time-management skills
Experience with regulatory writing, such as Investigator’s Brochures, INDs and CTAs, and a strong understanding of regulatory requirements
Meet your future team:
Pharmacology and Toxicology is a rapidly growing and valued team within Early Development at Intellia. Pharm/Tox is comprised of respected professionals with diverse expertise in both large pharma and small biotech settings. As part of the larger Research and Early Development (ReD) organization, we are a group of bright, fun, and team first people. Eager to move exciting projects forward, we are motivated by the opportunity to make an impact for patients!
The team is currently a mix of remote, hybrid, and onsite, and we are open to applicants working remotely for this role. Although in a virtual environment, the group has made it a priority to continue to foster a sense of community! You can expect to join a hardworking, collaborative environment.
Covid-19 Vaccination Policy: All Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. This requirement includes a booster dose once eligible. Requests for exemption for medical or sincerely held religious beliefs will be considered.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.