How You Will Achieve More with Intellia:

We are excited to welcome this new member to our growing team and company. This is both a strategic and hands-on role. If you are a strong and independent problem-solver, agile, detail-oriented with a strong technical background in synthetic oligonucleotides, and enjoy working in cross-functional teams, this is the role for you! As a Principal Scientist, you will work on various activities including:

• Setting up a new oligonucleotide process development laboratory and establish supply chains, workflows and operation to model manufacturing processes.
• Analyze data from manufacturing to inform, plan and execute process development projects (design, guide and execute sgRNA solid phase syntheses and downstream work-up/purification) that have the potential to yield process implementations for Intellia’s manufacturing processes (tech transfer packages).
• Strategize with the research organization and platform development to evaluate feasibility of innovative solutions for long-mer oligonucleotide synthesis and determine applicability for GMP manufacture.
• Act as manufacturing SME for external GMP manufacturing campaigns, development projects and vendor evaluation, interfacing with project management, quality and supply chain
• Prepare and support regulatory filings and answers to regulators; author process change documentation, reports, SOPs as well as technical documentation.
• Access the literature, regulatory guidances, databases, and technical documents to develop strategy, work plans, timelines in order to present data and findings to the larger group, cross functional teams and external partners.

Meet Your Future Team:

The Small Molecule Process Sciences Team (oligonucleotides and lipids) is a highly-motivated and lively group, with an innate curiosity to learn. You will report to the Associate Director, Nucleic Acid Therapeutics Development and Manufacturing. This team leads various important elements of the Technical Operations (CMC) department, including sgRNA and lipid manufacturing/process development and interfaces via project teams with analytical development, mRNA and lipid nanoparticle manufacturing, quality, chemistry, and platform development. While a growing team of currently two team members, you will work closely with the larger NTDM team, made up of 16 individuals.

Although Intellia currently is a partially virtual environment, the Human Resources team and Cultural Ambassadors have made it a priority to continue to foster a sense of community among the group. This includes virtual happy hours, team all hands, game nights, and more! You can expect to join a hardworking, collaborative environment and to work with dedicated and team-spirited group of people.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.