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Cell Therapy:
Scientist, T Cell Biology
Our Mission: Developing curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
At Intellia, we are committed to solving the complex challenges of making CRISPR/Cas9-based medicines a reality for patients suffering from genetic diseases and to create novel engineered cell therapies for immuno-oncological and autoimmune diseases.
Job Description:
Would you like to work in a company that is energetic, exciting, and fun? If so, Intellia may be the place for you! An exciting opportunity for an immunologist is available in our Gene Editing group where we leverage top-notch CRISPR technology to fully unleash the power of cell-based therapy for autoimmune and immuno-oncology indications. The ideal candidate would be versed in T cell biology with a strong expertise in experimental assays related to molecular and cell biology. Experience with in vivo models would be a plus.
Responsibilities:
- Design, implement, and troubleshoot experiments, both independently and in collaboration with colleagues, to reach desired goals
- Establish in vitro and in vivo assays to support T cell projects
- Communicate research and development findings with internal and external teams/partners in a clear and concise manner
- Diligent and timely documentation of experiments in ELN and reports
Qualifications:
- PhD in immunology, cell biology or related field with 0-2 years of postdoctoral experience. Industry experience would be a plus.
- Excellent interpersonal skills and ability to work efficiently and productively in a highly dynamic, scientifically rigorous, and fast-paced environment
- Ability to optimize complex protocols and assays to meet desired outcome
- Ability to quickly adapt and learn when faced with new challenges
- Strong motivation to deliver solid scientific results and focus on delivering on goals and timelines
- Strong organizational skills and the ability to handle multiple projects in parallel
- Effective verbal and written communication skills
- Strong problem-solving and analytical skills
- Hands-on experience with handling human T cells, T cell isolation techniques, activation and transduction of T cells, T cell expansion, multicolor flow cytometry for T cell characterization
- Experience with expansion of engineered T cells
- Strong background in human T cell biology and T cell-based assays, including proliferation assays, tetramer staining, cytotoxicity assays, intracellular flow cytometry staining or cytokine profiling assays by ELISA or MSD, cell activation marker analysis
- Development and optimization of purification methods for edited T cells
- Some experience with gene editing such as gene deletions and insertions
- General molecular biology techniques
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EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.