Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
Intellia is seeking a skilled and motivated Senior Scientist to lead the downstream function within the AAV process development group under Technical Operations. The ideal applicant will demonstrate track record of leading downstream processes development for AAV or other viral vector production. Experience with scalable downstream processes under GMP is a plus. Team work, versatility, and strong problem solving skills are required.
Design, execute and supervise AAV downstream process development for various unit operations including affinity and ion-exchange chromatography and tangential flow filtration.
Develop and perform pre-clinical scale up production processes based on QbD.
Cross-functional coordination and collaboration within Tech Ops and across the company to meet project goals and timelines.
Develop SOPs, provide SME support in technology transfers to strategic partners and CMOs, and support regulatory filings and related activities.
Provide high quality data and ELN documentation to drive decision making in the CMC team.
Operate and maintain multiple laboratory instruments.
Manage 2 direct reports to ensure the downstream function.
Bachelor’s degree in Biology, Virology, Chemical Engineering or related area with 10+ years of hands on industrial experience, or Master’s degree with 8+ years, or PhD with 2+ years.
Experience in process development plan and strategy is required.
Proficiency with experimental design, data analysis and development report for viral vector purification is required.
Hands-on Proficiency with filtration- or chromatography-based purification methods is required.
Experience in managing a small team, and excellent verbal and written communication skills.
Experience in virus purification under a GMP environment is a plus.
Experience with analytical assays including ddPCR/qPCR, ELISA, HPLC, DLS or CE-SDS is a plus.
Organized, detail-oriented, and a self-starter who continuously seeks innovative solutions.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.