Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How You Will Achieve More with Intellia:
We are excited to welcome this new member to our growing team and company. This is both a strategic and hands-on role. If you are a strong and independent problem-solver, agile, detail-oriented with a strong technical background in cell culture, analytic development, and potency assays, and enjoy working in cross-functional teams, this is the role for you! As a Senior Scientist, you will work on various activities including:
Design, develop, optimize, transfer, qualify and/or validate novel cell-based bioassays and immunoassays for potency.
Draft and review SOPs, technical reports, and regulatory documents
Transfer analytical methods internally or to contract laboratories manage internal experiments and trend internal method performance and specifications.
Lead bioassay comparability testing to support process changes and transfers. Data review, approval, analysis, graphing, reporting and presentation to internal and external audiences.
Act as a technical resource in investigations, health authority inquiries and regulatory filings
Familiarity with statistical concepts and design of experiments (DoE) related to functional cell-based assay development, optimization, and validation.
This is a unique role that will provide you with opportunities to impact ex vivo and in vivo applications by:
Developing, potency assays for cellular drug products, CRISPR/Cas9 components, lipid-nano particles, and AAV.
Collaborate with Intellia’s cross-functional platform development team and build a team to define, optimize and qualify potency and characterization assays.
Work to tech transfer assays to external testing labs.
Participate in drafting regulatory submissions.
What you will bring to the table:
PhD degree in Biochemistry, Cell & Molecular biology, or related disciplines with minimum 2+ years of experience; Master’s degree with minimum 8+ years of experience; BS with minimum 10+ years of experience in biotech or pharma industry with primary focus on biologics and/or gene and cell therapy.
Experience with primary culture of cell lines and primary cells, cell-based functional assays, and multi-color flow cytometry. Experience in designing and qualifying analytic test methods for cell-based therapies.
Direct experience in Analytical Development, Quality Control, or Process Development is a plus.
Meet Your Future Team:
The Potency Analytical Development team is a highly motivated and lively group with an innate curiosity to learn. You will report to the Associate Director, Potency Analytical Development. This team leads various important elements of the Technical Operations (CMC) department, including design of potency and characterization assays for in vivo and ex vivo drug products and drug product components.
Although Intellia currently is a partially virtual environment, the Human Resources team and Cultural Ambassadors have made it a priority to continue to foster a sense of community among the group. This includes virtual happy hours, team all hands, game nights, and more! You can expect to join a hardworking, collaborative environment and to work with dedicated and team-spirited group of people.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.