Translational Sciences:
Sr. Scientist, Flow cytometry- Early Development

Why Join Intellia? 

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. 

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. 

We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.   

How you will Achieve More with Intellia: 

We are excited to welcome a new senior scientist to our Early Development (eDev) team. We are seeking a highly skilled and motivated flow cytometrist. The primary responsibilities for this position will be to develop, optimize, and transfer flow cytometry-based cell quantitation and characterization methods for our expanding genome editing ex vivo pipeline. This person will report to the Associate Director of eDev and will work closely with our Research, Technical Operations, Regulatory, and Clinical teams as well as external partners. This role will combine laboratory experience characterizing edited cells with CRO oversight and management of transferring and validating clinical sample assays.

As a Sr. Scientist, you will:

  • Design, develop, and optimize flow cytometry-based cell kinetic assays to answer bioanalytical questions for ex vivo cell therapies

  • Troubleshoot protocols and increase method performance

  • Qualify flow cytometric assays for use in biological matrices focusing on immunophenotyping for cell therapies

  • Acquire and analyze data using a broad range of flow cytometry assays and be able to operate and maintain a variety of instruments

  • Lead cross-functional projects with our Cell Therapy Group, within eDev, and across the company at large

  • Compile assay qualifications, author bioanalytical reports, and communicate timelines and results to internal and external teams

  • Manage external CRO interactions including technical communications, assay transfers, method qualifications and validations, report drafting and review, and sample analysis

  • Contribute to regulatory documents to advance drug development

  • Contribute to data driven decisions and strategies to understand drug efficacy, safety, and mechanism of action

About You:

You are a flow cytometry expert with hands on experience and in-depth scientific knowledge of multi-parameter flow cytometric assay development, validation, and clinical sample analysis. You have knowledge on consistent gating and data analysis for whole blood, frozen PBMC, and other cell types. You have interacted with or managed external CRO relationships and projects. You are an independent, innovative scientist, and also a team player with excellent time management and communication skills.

You hold a doctorate in a life sciences field with 2-6 years of industry experience. Alternatively, you hold a master’s degree in a similar field with at least 8 years of industry experience or a bachelor’s degree in a similar field with at least 10 years of industry experience. You are interested in continuously learning new analysis methods for cell therapies and translating research methods into ones appropriate for clinical sample analysis.

Meet your future team:

The eDEV team is a self-motivated and lively group, with an innate curiosity to explore and deliver. We are bench scientists with expertise in biochemical assays, mass spectrometry, protein quantitation, and oligonucleotide quantitation. We are pharmacologists, toxicologists, and study coordinators. The team characterizes our therapeutics and their components. We develop methods and analyze bioanalytical samples inhouse and also translate research assays to validated, clinical ones in support of patient sample analysis. You can expect to join a hardworking, collaborative environment.

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Covid-19 Vaccination Policy: Effective Monday, January 3, 2022, all Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. Requests for exemption for medical or sincerely held religious beliefs will be considered.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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