Archives

In Vivo Therapy

June 29, 2020 9:47 am Published by

Meaning “within the living”, this type of therapy is administered directly into the patient, targeting the cells and editing the... View Article

Informed Consent

October 14, 2020 11:24 am Published by

In a clinical trial setting, informed consent means that patients considering volunteering to enroll receive information and consent to the... View Article

Insertion

October 14, 2020 11:25 am Published by

Insertion of a new DNA sequence into the genome to manufacture a desired protein using a gene editing technology, such... View Article

Knockdown

October 14, 2020 11:27 am Published by

Reduction of protein, with the goal of achieving a therapeutic effect, as a result of a gene or genome editing... View Article

Knockout

June 29, 2020 10:35 am Published by

Inactivation/deletion of a DNA sequence using a gene editing technology, such as the CRISPR/Cas9 system. This is the type of... View Article

Lipid Nanoparticle

October 14, 2020 11:28 am Published by

Also known as LNP. LNPs are fat-based molecules that are the basis of Intellia’s CRISPR/Cas9 delivery platform. In Intellia’s experimental... View Article

Liquid Cancers

October 14, 2020 11:28 am Published by

Also known as blood cancers or hematological malignancies. Cancers like leukemia, lymphoma and myeloma that originate in blood, bone marrow... View Article

Messenger RNA

October 14, 2020 11:29 am Published by

Also known as mRNA. mRNA, which encodes the Cas9 protein, is one of the components comprising Intellia’s CRISPR/Cas9 LNP delivery... View Article