Multiplex Editing
October 14, 2020 11:28 amModifying multiple genes simultaneously.
Archives
Murine
October 14, 2020 11:29 amResearchers often use a murine, or mouse, model for early preclinical testing of experimental treatments. Studies typically progress from a... View Article
Non-Human Primate
October 14, 2020 11:29 amAlso known as NHP. Preclinical studies advance from rodent to higher species, such as NHP, studies prior to entering clinical... View Article
Pathogen
October 14, 2020 11:29 amA pathogen is any of any foreign substance that the immune system does not recognize and tries to fight off... View Article
Pharmacodynamics
October 14, 2020 11:30 amSometimes paired with pharmacokinetics to form the abbreviation, PKPD. Pharmacodynamics is how your body reacts to the experimental treatment. PKPD... View Article
Pharmacokinetics
October 14, 2020 11:30 amSometimes paired with pharmacodynamics to form the abbreviation, PKPD. Pharmacokinetics is how an experimental treatment moves through the body. PKPD... View Article
Prekallikrein B1 Gene
October 14, 2020 11:30 amAlso known as KLKB1 gene. Knocking out this gene is expected to reduce kallikrein activity, which is involved in the... View Article
Regenerative Medicine
June 29, 2020 10:36 amUsing a combination of tissue engineering and molecular biology to treat genes – the root causes of gene-based diseases and... View Article
Regulatory Authority
October 14, 2020 11:31 amAlso known as a regulatory agency. The U.S. FDA and the U.K. MHRA are examples of local regulatory authorities responsible... View Article
Repair
October 14, 2020 11:32 amCorrection of “misspelled” disease-driving DNA sequence using a CRISPR/Cas9-based gene editing therapy.